Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty

Launched by HENRY FORD HEALTH SYSTEM · Feb 12, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how effective different antimicrobial washes are at reducing the presence of a bacteria called C. Acnes in patients undergoing shoulder replacement surgery. Participants will be randomly placed into one of four groups: one group will receive a special antimicrobial wash called Xperience, another will use hydrogen peroxide, a third will use betadine, and the last group will not receive any wash at all. The goal is to see if using these antimicrobial solutions after the surgery can lower the number of patients who still show signs of C. Acnes, which can lead to infections.

To be eligible for this trial, participants must be at least 18 years old, scheduled for shoulder replacement surgery, and have tried other treatments for at least six weeks without success. However, those with certain conditions like previous shoulder infections, certain types of cancer, or specific autoimmune diseases won't be able to participate. If you join the study, you will receive one of the treatments after your surgery, and researchers will monitor how well each option works. This trial is not yet recruiting participants, so more information will be available as it progresses.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Indicated and scheduled for primary shoulder arthroplasty.
• • Chronic severe glenohumeral osteoarthritis, avascular necrosis, post traumatic osteoarthritis, rotator cuff arthropathy,
• • Ability to read and understand English
• • Age ≥18 years
• • Patient failed ≥6 weeks of conservative treatment, which included non-steroidal anti-inflammatory drugs (NSAIDS)
• Exclusion Criteria:
• • Patient with history of prior native shoulder septic arthritis or infection
• • Prior surgery of affected shoulder
• • Proximal Humerus Fracture
• • Active infection
• • Cancer
• • Autoimmune and rheumatologic disorders, including rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus
• • History of allergic reaction to citric acid-derived products