Impact of Cannabinoids on Menopause Symptoms

Launched by WASHINGTON STATE UNIVERSITY · Feb 12, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how certain hemp-derived cannabinoids may help with symptoms related to menopause and perimenopause, which are stages in a woman's life when hormone levels change and can cause various symptoms like hot flashes, mood swings, and sleep disturbances. The trial is currently recruiting women aged 40 to 60 who identify as female at birth and are experiencing these symptoms. To participate, you need to be able to give informed consent, have stable medication routines, and not have used cannabis regularly in the past year.

If you join this study, you'll be asked to use a smartphone and have a reliable internet connection for meetings over Zoom. Throughout the trial, you won't be able to take certain medications, including some antidepressants or anti-anxiety drugs, and you should avoid heavy alcohol use. This is to ensure the research focuses on the effects of cannabinoids without other factors interfering. If you meet the eligibility criteria, this trial could be a valuable opportunity to explore potential relief for menopause symptoms while contributing to important research.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • designated female at birth
• • 40-60 years of age
• • able to give informed consent (no intellectual disability)
• • stable pharmacotherapeutic regimen, no change in the past 3 months
• • abstinent from regular cannabis use (\<1x/month) for past year, and willing to abstain from use for 3 months
• • abstinent for supplements, don't add any supplements (no changes in past 3 months)
• • own a smartphone
• • have access to Zoom on a secure, stable internet connection
• • perimenopausal or menopausal
• Exclusion Criteria:
• • currently taking anti-depressant, anti-anxiety, and/or antipsychotic medication
• • severe depression, neurovegetative symptoms, or current suicidality
• • psychosis or family history of psychosis
• • pregnant or breastfeeding
• • chemotherapy
• • hypotension
• • drug testing for work or other reasons
• • illicit drug use in past 3 months (cannabis not illicit)
• • heavy alcohol use (4 drinks more than 4x/week)
• • international/air travel planned for more than one week in the next 3 months