Atrial Strain in Septic Shock
Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Feb 11, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "Atrial Strain in Septic Shock," is studying how well certain echocardiography (a type of ultrasound for the heart) techniques can measure heart function in patients experiencing septic shock, a serious condition that can lead to organ failure and is often life-threatening. The researchers want to compare two different software programs used to analyze heart images to see if they provide consistent results. They will also look at a new technology called AutoStrain to see how reliable it is when different people analyze the images. The goal is to improve how heart function is measured in critically ill patients, which can help doctors make better treatment decisions.
To be eligible for this study, participants must be adults over 18 years old who have been admitted to critical care for septic shock and have had a transthoracic echocardiogram (TTE) as part of their treatment. However, individuals who are pregnant, have significant heart valve problems, or certain heart rhythm issues at the time of the TTE will not be included. Since this study uses existing heart images, participants can expect that their past echocardiograms will be reviewed, and no new procedures will be performed specifically for this study. Overall, the findings from this trial may lead to more standardized and accurate assessments of heart function in patients facing severe illness.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age: \>18 years
- • Adult patients admitted to critical care for septic shock (SEPSIS-3 definition)
- • TTE performed as part of medical management
- • No objection to data usage
- Exclusion Criteria:
- • Pregnancy
- • Moderate to severe valvular regurgitation/stenosis (\>grade 2)
- • Ventricular or supraventricular tachyarrhythmia (HR \>140 bpm) at the time of TTE
- • Poor echogenicity preventing LAS measurement
- • Mechanical circulatory support
- • Pacemaker dependence
- • Patients under guardianship
About Centre Hospitalier Universitaire, Amiens
The Centre Hospitalier Universitaire (CHU) Amiens is a leading academic medical center in France dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on multidisciplinary collaboration, CHU Amiens integrates patient care, education, and research to enhance treatment outcomes and improve patient quality of life. The institution is committed to ethical standards and regulatory compliance in its clinical research endeavors, aiming to contribute significantly to the medical community and the development of new therapeutic approaches. By fostering partnerships with various stakeholders, CHU Amiens strives to translate scientific discoveries into practical applications that benefit patients and healthcare systems alike.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Salouel, , France
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported