Efficacy of Propofol-Ketamine and Sevoflurane in Children Undergoing Magnetic Resonance Imaging

Launched by KOCAELI CITY HOSPITAL · Feb 12, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness of two different anesthesia methods for young children undergoing magnetic resonance imaging (MRI) at Kocaeli City Hospital. The trial compares the use of a combination of propofol and ketamine, which are given through an IV, against sevoflurane, which is inhaled through a face mask. The goal is to find out which method allows children to stay still during the MRI while also ensuring a safe and quick recovery afterward.

To be eligible for this study, children aged between 3 months and 10 years who are scheduled for an MRI may participate, as long as they are generally healthy and classified as ASA I-II (which means they are not facing serious health issues). However, children with specific health conditions, allergies to the study medications, or behavioral problems that could affect the procedure cannot take part. If your child is eligible and chooses to participate, they will receive one of the two anesthesia methods during their MRI, and the researchers will monitor their safety and recovery closely. This trial aims to ensure that children can undergo necessary imaging safely and comfortably.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Ages 3 months to 10 years.
• • Classified as ASA I-II according to the American Society of Anesthesiologists (ASA) classification.
• • Patients scheduled for MRI at Kocaeli City Hospital MRI unit.
• Exclusion Criteria:
• • Families or children who do not consent to participate in the study.
• • Patients with allergies to ketamine, propofol, midazolam, or sevoflurane.
• • Patients with known pulmonary or cardiac diseases.
• • Patients with known congenital craniofacial or neck anomalies.
• • Patients dependent on oxygen therapy.
• • Patients with a recent respiratory tract infection within the past 2 weeks.
• • Patients requiring tracheal intubation, laryngeal mask, or ventilator support.
• • Patients at risk of upper airway obstruction.
• • Patients with behavioral problems.
• • Patients with gastroesophageal reflux disease.
• • Patients with lethargy, stupor, or unresponsiveness to stimuli due to any cause
• • Patients with active use of antiepileptic or antipsychotic medications