IVC Collapsibility Index or CVP as a Predictor of Fluid Responsiveness in Pediatric Sepsis

Launched by TANTA UNIVERSITY · Feb 12, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how to best manage fluid treatment for young children suffering from severe infections called sepsis, specifically those caused by a condition known as a perforated viscus, where there is a hole in the intestine. The researchers are comparing two ways to guide fluid treatment: one method uses a measurement called central venous pressure (CVP), and the other uses the inferior vena cava (IVC) collapsibility index, which looks at how well a blood vessel in the abdomen responds to fluid. The main goal is to see how these methods affect how long children stay in the hospital, as well as any complications that may arise during their treatment.

To participate in this trial, children aged 1 to 5 years who are experiencing septic shock due to a perforated viscus can be included. However, some children may not qualify, such as those who are obese, have certain heart conditions, or have had previous major surgeries. Those who join the study can expect to receive fluid resuscitation based on one of the two methods before, during, and after their surgery. It's important to note that the trial is not yet recruiting participants, meaning it hasn’t started enrolling patients just yet.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Pediatric patients aged 1 to 5 years presented with septic shock due to perforated viscus according to definition of the American College of Critical Care Medicine and International Pediatric Sepsis Consensus.
• Exclusion Criteria:
• • Refusal of the parents to participate in the study
• • Obesity
• • Congenital heart diseases
• • Severe arrythmias
• • Patients developed moderate to severe ARDS
• • Massive ascites
• • Previous abdominal surgery
• • Previous cardiothoracic surgery