Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia
Launched by CAIRO UNIVERSITY · Feb 14, 2025
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how a technique called rib mobilization might help patients with pneumonia who need to be on a mechanical ventilator, which is a machine that helps them breathe. The researchers want to see if rib mobilization can improve the way patients are able to breathe on their own compared to standard chest therapy. They will measure things like how fast a patient breathes and how much oxygen they are getting. The study will also track how long patients stay in the intensive care unit (ICU) and how successful they are at being weaned off the ventilator.
To be eligible for this trial, participants need to be between 40 and 50 years old, diagnosed with pneumonia, and require mechanical ventilation. They should also have stable oxygen levels and blood pressure. However, those with certain serious conditions, like unstable heart issues or severe neurological problems, will not be included. This trial is not yet recruiting participants, but it aims to help improve care for patients with pneumonia in the future by understanding the potential benefits of rib mobilization.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Patient's age ranged from 40- 50 years old from both genders.
- • 2. Diagnosed with pneumonia and need invasive mechanical ventilation support.
- • 3. Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O).
- • 4. mean arterial pressure \> 75 mmHg and urine output \> 1 mL/kg/h;
- • 5. Patients with Glasgow coma scale (GCS) \> 8T
- • 6. Unconscious and semi-conscious patients. -
- Exclusion Criteria:
- • 1. Unstable hemodynamics
- • 2. Unstable neurological problems e.g. (epileptic seizures -hyperthermia).
- • 3. Unstable chest wall e.g. (multiple rib or vertebral fractures)
- • 4. Increase intracranial pressure (\>20 mmHg for \>5 min).
- • 5. Undrained pneumothorax, recent pulmonary surgery
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Cairo, , Egypt
Patients applied
Trial Officials
Azza Abd El Aziz Abd El Hady, professor
Study Chair
Cairo University
Mohammed Abd Hakim El-Nadi, professor
Study Director
Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported