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Search / Trial NCT06835894

Trending Ability of End-Tidal Capnography to Reflect Arterial Carbon Dioxide Changes in One-Lung Ventilation

Launched by KOÇ UNIVERSITY · Feb 14, 2025

Trial Information

Current as of July 01, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is investigating whether measuring carbon dioxide in a patient’s breath (called end-tidal CO₂ or ETCO₂) can accurately reflect changes in carbon dioxide levels in the blood (known as arterial CO₂ or PaCO₂) during lung surgery. In this type of surgery, patients often use "one-lung ventilation," which means one lung is used for breathing while the other is temporarily deflated. This can lead to changes in carbon dioxide levels that are usually monitored by taking blood samples. The study aims to see if the trends in ETCO₂ align with those in PaCO₂ over time, which could help doctors reduce the number of blood tests needed.

To be eligible for this trial, patients must be undergoing thoracoscopic lung surgery with one-lung ventilation and require a small tube in an artery for monitoring blood pressure. However, patients with chronic lung diseases, pulmonary hypertension, or systemic infections will not be included. Participants will have their blood carbon dioxide levels compared to their breath measurements at the same time, and additional health information like heart rate and body temperature will also be monitored. This research could lead to a simpler and less invasive way to monitor carbon dioxide levels during lung surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients undergoing thoracoscopic lung surgery with one-lung ventilation
  • Patients requiring invasive arterial blood pressure monitoring
  • Exclusion Criteria:
  • Chronic obstructive pulmonary disease (COPD)
  • Pulmonary hypertension
  • Systemic infection

About Koç University

Koç University, a leading multidisciplinary research institution located in Istanbul, Turkey, is dedicated to advancing healthcare through innovative clinical research. With a commitment to excellence in education and research, the university fosters collaboration among experts in various fields, aiming to translate scientific discoveries into practical applications that improve patient outcomes. Koç University’s clinical trial initiatives are characterized by rigorous methodologies, ethical standards, and a focus on addressing pressing health challenges, positioning it as a pivotal player in the global research landscape.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported