Impact of Anesthesia, Positive Pressure Ventilation and Modality of Imaging on the Echocardiographic Assessment of the Severity of Aortic Regurgitation

Launched by UNIVERSITY OF LIEGE · Feb 14, 2025

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ClinConnect Summary

This clinical trial is looking at how different ways of imaging the heart can affect the assessment of aortic regurgitation, which is a condition where the heart's aortic valve doesn't close properly, causing blood to flow back into the heart. Researchers are comparing two types of echocardiograms (heart ultrasounds): one done on the chest (trans-thoracic echo or TTE) before patients receive anesthesia, and another done through the esophagus (trans-esophageal echo or TEE) after anesthesia has started. The goal is to understand how anesthesia and breathing support during surgery might change the way doctors evaluate the severity of aortic regurgitation.

To be eligible for this study, participants need to have a known degree of aortic regurgitation and be scheduled for cardiac surgery where a TEE will be performed. Some people may not qualify if they have certain heart conditions or are in a critical state before surgery. If you decide to participate, you will undergo both types of echocardiograms, allowing researchers to gather important information that could help improve heart assessments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Known aortic regurgitation of any grade
• • Scheduled for a cardiac surgery procedure during which a trans-esophageal echo is planned.
• Exclusion Criteria:
• • Non sinus rhythm
• • Mitral regurgitation more than mild.
• • Pre-operative critical state (according to the definition of the EuroSCORE II)
• • Presence of a prosthetic aortic valve
• • Contra-indication to trans-esophageal echo