PEEP Vs. ZEEP in Out-of-Hospital-Cardiac-Arrest

Launched by MUEHLENKREISKLINIKEN, MKK · Feb 15, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different ways of providing breathing support to adult patients who have experienced an out-of-hospital cardiac arrest (OHCA), which is when the heart suddenly stops beating outside of a hospital. The study compares a technique called positive-end-expiratory-pressure (PEEP) to zero-end-expiratory-pressure (ZEEP) during resuscitation efforts. PEEP helps keep the airways open, while ZEEP allows them to close completely. The goal is to see which method helps more patients regain their heartbeat and improve their chances of survival.

To participate in this trial, individuals must be at least 18 years old and have had a non-traumatic cardiac arrest, meaning their heart stopped for reasons other than an injury. They should also require mechanical breathing support. Unfortunately, those under 18 years old, those with injuries causing their cardiac arrest, or anyone who has decided against resuscitation will not be eligible. The trial is not yet recruiting participants, but if eligible, participants can expect to contribute to important research that may help improve care for future patients in similar situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults \>= 18 years
• • non-traumatic OHCA
• • mechanical ventilation via airway device
• Exclusion Criteria:
• • Patients \< 18 years,
• • traumatic cause of OHCA,
• • no cardiac arrest, withholding of resuscitation (e.g. Do-Not-Resuscitate orders)