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Search / Trial NCT06837636

During Chest Surgery, One Lung is Isolated From Ventilation to Improve Visibility, With Carbon Dioxide Introduced Between the Lung and Chest Wall (Capnothorax): the Study Seeks to Optimize Ventilation Through Esophageal Pressure Measurement, Reducing Respiratory Complications.

Launched by CARDARELLI HOSPITAL · Feb 19, 2025

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Capnothorax One Lung Ventilation Esophageal Pressure Thoracic Surgery

ClinConnect Summary

This clinical trial is investigating a new way to improve safety and effectiveness during chest surgeries, specifically when only one lung is used for ventilation. To help surgeons see better while they operate, a small amount of carbon dioxide is introduced into the space between the lung and the chest wall, a procedure known as capnothorax. The goal is to measure the pressure in the esophagus, which helps us understand how well the lungs are working and to adjust the ventilation settings accordingly. This technique aims to provide the right amount of air to the lungs, reduce the risk of lung damage, and improve breathing during and after the surgery.

To participate in this study, individuals must be over 18 years old and scheduled for robotic thoracic surgery that will use capnothorax. However, those with certain heart or lung conditions, or who have severe respiratory issues, may not be eligible. Participants can expect to have some basic health information collected beforehand, as well as detailed measurements during the surgery to monitor their respiratory function and overall health. This research aims to enhance patient safety and improve recovery after surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age over 18 years • Patients to undergo robotic thoracic surgery with capnothorax
  • Exclusion Criteria:
  • Pre-existing cardiac and/or pulmonary pathologies resulting in an ASA \> 3
  • Contraindications to the placement of a nasogastric tube
  • Severe COPD (stage 3 or 4)
  • Emergency thoracotomy or sternotomy for surgical complications

About Cardarelli Hospital

Cardarelli Hospital is a leading healthcare institution renowned for its commitment to excellence in patient care and clinical research. Located in Naples, Italy, the hospital is equipped with state-of-the-art facilities and a multidisciplinary team of healthcare professionals dedicated to advancing medical knowledge and improving treatment outcomes. As a clinical trial sponsor, Cardarelli Hospital focuses on innovative research initiatives that aim to address critical healthcare challenges, enhance therapeutic options, and contribute to the global medical community. With a strong emphasis on ethical standards and patient safety, Cardarelli Hospital plays a pivotal role in facilitating clinical trials that drive scientific progress and foster collaboration among researchers and healthcare providers.

Locations

Napoli, , Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported