Trend Correlation Between End-Tidal and Arterial Carbon Dioxide During Laparoscopic Surgery in Trendelenburg Position

Launched by KOÇ UNIVERSITY · Feb 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a measurement called "end-tidal carbon dioxide" (ETCO₂), which comes from the air you breathe out, can accurately show the level of carbon dioxide in your blood during laparoscopic surgery. In this type of surgery, patients are often positioned with their heads tilted down to help doctors see better. This position can change how carbon dioxide behaves in the body. Currently, doctors have to draw blood to check carbon dioxide levels, but if we find that ETCO₂ can provide reliable information, it may reduce the need for blood tests.

To participate in the trial, you need to be scheduled for laparoscopic surgery in the Trendelenburg position and will have a small tube placed in an artery for routine monitoring. This study will include 79 patients and will involve comparing ETCO₂ readings with blood samples taken during surgery. Participants will also have their heart rate, blood pressure, and temperature monitored. The goal is to see if we can use ETCO₂ readings as a simpler and less invasive way to track carbon dioxide levels during this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Scheduled to undergo laparoscopic surgery in the Trendelenburg position
• • Planned to receive invasive arterial blood pressure monitoring as part of routine clinical care (independent of the study)
• Exclusion Criteria:
• • Chronic obstructive pulmonary disease
• • Pulmonary hypertension
• • Active systemic infection