Ultrasonographic Patterns and Pathological Correlation in the Diagnosis of Subcutaneous Nodules

Launched by MAHIDOL UNIVERSITY · Feb 17, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how ultrasonography, a safe and non-invasive imaging technique, can help doctors diagnose subcutaneous nodules, which are lumps found just under the skin. The study aims to see if the information gathered from the ultrasound can accurately identify different conditions that cause these nodules when compared to results from skin biopsies, which are tests where a small sample of tissue is taken for examination.

To participate in this study, individuals must be 18 years or older and have subcutaneous nodules that need to be examined further. Participants will undergo an ultrasound scan to look at their nodules before having a biopsy. However, certain people may not qualify, such as those with specific skin diseases or conditions that could interfere with the ultrasound results. Overall, this study seeks to improve the way doctors diagnose skin conditions, making it easier and safer for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 years and older who presented with subcutaneous nodules
• • Indicated for pathological examination for disease diagnosis.
• • Patients with subcutaneous nodules located in areas where a tissue sample can be taken down to the fat layer.
• • Patients who agree to participate in the project by signing the consent form.
• Exclusion Criteria:
• • Presence of inflammation or other tumors that can mimic panniculitis, such as painful lipomas, cellulitis, and leg interstitial edema.
• • Patients with diseases that significantly alter the structure of the skin or subcutaneous tissue, such as scleroderma or severe edema.
• • A history of previous treatments in the area of the subcutaneous mass (e.g., surgery, radiation therapy, or high-dose steroid treatment) that may interfere with ultrasound results.
• • Patients with lesions on the head or mucous membranes of the body.
• • Pregnant or breastfeeding patients.
• • Presence of wounds or open sores in the area to be examined with ultrasound.
• • A history of coagulopathy (blood clotting disorders).
• • Patients with metal implants in the area of interest that may interfere with ultrasound imaging.
• • Participants who refuse or withdraw from the study.