ClinConnect ClinConnect Logo
Search / Trial NCT06839443

Deep Learning in the Detection and Prediction of Hydroxychloroquine Maculopathy

Launched by CENTRO HOSPITALAR DE LISBOA CENTRAL · Feb 17, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Hidroxicloroquine Maculopathy Hidroxicloroquine Toxicity

ClinConnect Summary

This clinical trial is studying how advanced computer technology, called deep learning, can help detect and predict eye problems caused by long-term use of hydroxychloroquine, a medication often prescribed for conditions like lupus or rheumatoid arthritis. Many patients who take this medication may develop retinal toxicity, which can lead to vision problems. Early detection is crucial because it can help prevent serious damage to the eyes. The trial aims to automate the analysis of eye tests, making it easier and quicker to spot any issues.

To participate in this study, you need to be at least 65 years old and have been taking hydroxychloroquine for more than 10 years. Unfortunately, if you have other eye diseases that could confuse the results, you won't be eligible. If you join the trial, you will have your eye images collected through routine screenings, which will help researchers understand how to improve early detection of these eye problems. The study is currently recruiting participants, and it’s a great opportunity to contribute to important research that could benefit many patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with \> 10 years of HCQ intake
  • Exclusion Criteria:
  • Patients with ocular diseases that might mimic HCQ maculopathy or interfer with HCQ maculopathy screening

About Centro Hospitalar De Lisboa Central

Centro Hospitalar de Lisboa Central (CHLC) is a leading healthcare institution in Portugal, dedicated to providing high-quality medical care and advancing clinical research. As a prominent sponsor of clinical trials, CHLC plays a crucial role in the development of innovative therapies and treatments across various medical fields. The hospital is committed to fostering collaborations with academic institutions and industry partners, ensuring rigorous adherence to ethical standards and regulatory guidelines. With a multidisciplinary team of experienced researchers and healthcare professionals, CHLC aims to enhance patient outcomes and contribute to the global body of medical knowledge through its comprehensive clinical research initiatives.

Locations

Portugal, , Portugal

Patients applied

0 patients applied

Trial Officials

Rita Anjos, MD

Study Chair

ULS São José

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported