Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity

Launched by MIAMI UNIVERSITY · Feb 18, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how physical inactivity affects our body’s ability to control blood sugar and blood vessel health, especially in people with different fitness levels and body fat amounts. Researchers want to understand if being fit or having more body fat changes how well someone can recover their blood sugar control after a period of being less active. They will also look at how blood vessel function plays a role in this recovery. The goal is to gather valuable information that can help improve health outcomes for those with metabolic disorders.

To participate, individuals need to be between 18 to 40 years old and able to ride an electric scooter for at least 10 minutes. They should be physically active, walking more than a mile each day and getting over 7,000 steps daily. Participants must have a stable body weight and specific levels of fitness and body fat. During the study, participants will go through three phases: a week of normal activity, a week of reduced physical activity, and then a week of returning to normal activity. Researchers will monitor their blood sugar levels and blood vessel function throughout the trial. This study is not yet recruiting participants, but it aims to shed light on important health issues related to physical inactivity.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Males and females 18 to 40 years of age.
• • Ability to safely ride an electric scooter (e-scooter) for at least 10 minutes.
• • Active (\>7000 steps per day, walking \> 1 mile a day outside)
• • Stable body weight for at least 1 year
• • aerobic fitness level, CRF is \< 9 and \>14 METS
• • Visceral adipose tissue \<130 cm2 or ≥130 cm2 for men and \<100 cm2 or ≥100 cm for women
• Exclusion Criteria:
• • Any injury preventing them from exercising regularly at the time of the screening.
• • Implantable defibrillator or pacemaker
• • Active cancer
• • Alcohol or drug abuse
• • Use of an assistive walking device
• • Presence of significant signs/symptoms of cardiovascular, metabolic, or pulmonary disease (determined from the American College of Sports Medicine (ACSM) Health History Questionnaire)
• • Daily vitamin consumption of \> 500mg per day during the study
• • Acetaminophen or aspirin use during the study