Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2

Launched by CAIRO UNIVERSITY · Feb 19, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how effective Botulinum Toxin A injections are in treating a condition known as gingival recession, specifically types RT1 and RT2, in the lower front teeth. Gingival recession occurs when the gum tissue pulls back, exposing more of the tooth or its root, which can lead to sensitivity and other dental issues. The researchers want to see if using Botulinum Toxin A, along with a surgical technique called a coronally advanced flap, is better than just using the surgical technique alone.

To participate in this trial, individuals must be at least 18 years old, have healthy gums, and be motivated to maintain good oral hygiene. Those with certain conditions, such as pregnant or breastfeeding women, smokers, or individuals with specific dental restorations, will not be eligible. Participants will undergo a series of procedures, including the injection and surgery, and will be monitored for changes in gum tissue over three and six months. This study aims to improve treatment options for people experiencing gum recession.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Single or multiple RT1, RT2 GR patient
• • patients ≥18 years
• • systemically healthy, full mouth plaque score, full mouth bleeding score ≤ 15% after phase I therapy
• • clinical indication and/or patient request for recession coverage
• • well motivated patients, maintaining oral hygiene throughout study
• Exclusion Criteria:
• • Pregnant or lactating women
• • Smokers' patients
• • Teeth with cervical restorations/abrasion.
• • Patients had a systemic condition affect blood components and healing