Accuracy of Lactate Meter in GSDIa

Launched by CONNECTICUT CHILDREN'S MEDICAL CENTER · Feb 20, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to see if portable devices that measure lactate levels at home are accurate for patients with Glycogen Storage Disease Type Ia. Lactate is a substance in the blood that can indicate how well the body is using sugar. The study will compare the results from these home devices to the results from traditional lab tests. Additionally, they will evaluate a specific glucometer, called the Accu Chek Guide, to see if it provides accurate readings for this group of patients.

To participate in this study, individuals must have a confirmed diagnosis of Glycogen Storage Disease Type Ia, either through a liver biopsy or genetic testing. The trial is open to people of all ages, from newborns to adults. Participants will be recruited from the Connecticut Children's Emergency Department or hospital admissions. Parents or guardians will need to provide consent for children, while adults will need to agree to participate themselves. If you or your child are interested and meet the eligibility criteria, this could be a valuable opportunity to help improve the understanding of lactate monitoring in this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with diagnosed/confirmed (by liver biopsy or genetic testing) Glycogen Storage Disease Type Ia (ICD 10 code: E74.01).
• • Connecticut Children's Emergency Department visit and/or admission to Connecticut Children's during time study is active
• • For pediatric participants: Ability of child's parent/legal guardian to understand and the willingness to sign a written informed consent document
• • For adults: Ability to understand and the willingness to sign a written informed consent
• Exclusion Criteria:
• • Patients with Glycogen storage disease unspecified 74.00, or Ib
• • Patients not meeting inclusion criteria