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Search / Trial NCT06844448

The Effect of Different Risk Factors on the Success Rate of VPT

Launched by SEMMELWEIS UNIVERSITY · Feb 19, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how effective different treatments for dental pulp issues are in keeping the pulp, or inner part of a tooth, healthy after it's been exposed. The treatments being evaluated include direct pulp capping, partial pulpotomy, and total pulpotomy. The goal is to see which method works best and how factors like age might affect the results. This study is open to adults over 18 who have at least one tooth with a pulp chamber that has been opened during a dental procedure. To be eligible, the tooth must still respond to cold sensitivity tests and be restorable.

Participants in the study will be monitored for up to four years to see how well their treatment works, using both clinical exams and X-rays. The researchers will also look to see if older adults prefer these vital pulp therapies over traditional root canal treatment. If you or someone you know has a tooth that fits the criteria, this study may provide valuable insights and contribute to better dental care practices.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients over 18 years of age who have at least one tooth with a pulp chamber that has been opened during a dental procedure or is likely to be opened during restoration of the tooth
  • The tooth is responsive to a sensitivity test with cold spray
  • The coronal part must be restorable
  • The periodontal depth around the tooth should be 0 according to the Dental Practicality Index Periodontal Treatment Need, i.e. the probing depth around the tooth should not be greater than 3.5 mm
  • Exclusion Criteria:
  • Internal/external resorption in the tooth
  • If the root development of the tooth is not yet complete or if it is a deciduous tooth
  • Absolute isolation cannot be performed during the procedure
  • If pulp exposure does not occur even after complete removal of caries
  • The crown of the tooth cannot be restored
  • Periodontium surrounding tooth affected by moderate/severe marginal periodontitis (probing depth deeper than 3.5 mm)
  • Pulp exposure due to traumatic injury
  • Baseline radiograph shows signs of severe pulp palcification
  • Periapical lesion is around the root (Periapical index of the tooth \>2)

About Semmelweis University

Semmelweis University, located in Budapest, Hungary, is a prestigious institution renowned for its commitment to advancing medical education, research, and healthcare innovation. As a prominent clinical trial sponsor, the university leverages its extensive expertise in various medical fields to conduct rigorous clinical studies aimed at improving patient outcomes and enhancing therapeutic strategies. With a focus on ethical standards and scientific excellence, Semmelweis University collaborates with a network of healthcare professionals and researchers to translate groundbreaking discoveries into practical applications, ultimately contributing to the global advancement of medical science.

Locations

Budapest, , Hungary

Patients applied

0 patients applied

Trial Officials

János Vág, DMD, PhD

Study Chair

Semmewleis University, Department of Restorative Dentistry and Endodontics

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported