Randomized Clinical Trial Aimed at Comparing Unclamped Robotic Partial Nephrectomy With or Without Renorrhaphy

Launched by REGINA ELENA CANCER INSTITUTE · Feb 20, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a surgical approach for patients with kidney cancer. Specifically, it compares two methods of a surgery called robotic partial nephrectomy, where part of the kidney is removed. The trial aims to see if a technique that doesn't use clamps during the surgery helps minimize damage to the kidney caused by reduced blood flow, known as ischemia. This could potentially lead to better outcomes for patients undergoing this procedure.

To be eligible for the trial, participants must be at least 18 years old and have been diagnosed with a specific type of kidney cancer that hasn't spread. They should also be suitable candidates for the robotic surgery and agree to participate and follow the study's procedures. During the trial, participants can expect to receive either of the two surgical methods and will be closely monitored throughout the process. It’s important to note that individuals with certain prior kidney issues or multiple kidney tumors cannot participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age ≥ 18 years;
• • radiological diagnosis of organ-confined renal neoplasm (cT1-2 cN0);
• • patient who is a candidate, due to personal or tumor characteristics, for ocRPN intervention;
• • compliant patient, able to follow the procedures/follow-up;
• • patient who agrees to participate in the clinical study and the planned randomization, by signing the informed consent.
• Exclusion Criteria:
• • preoperative evidence of unilateral/bilateral synchronous renal neoplasms;
• • personal history of renal surgery for benign or malignant pathology.