Retinal Investigation Using Optos OCT Device

Launched by OPTOS, PLC · Feb 20, 2025

Keywords

ClinConnect Summary

This clinical trial, called the "Retinal Investigation Using Optos OCT Device," is designed to study different eye conditions that affect vision, specifically Age-Related Macular Degeneration (AMD), Retinitis Pigmentosa (RP), and Diabetic Retinopathy. The researchers will use a special imaging technique called Optical Coherence Tomography (OCT) to take detailed pictures of the retina, the light-sensitive tissue at the back of the eye. This study will also include a control group of participants who do not have any eye diseases, helping to compare and understand the impact of these conditions on the retina.

To join this trial, participants must be at least 18 years old and able to understand the study's purpose and procedures. People with certain eye diseases affecting at least one eye, such as early or late stages of AMD, RP, or diabetic retinopathy, are welcome to participate. However, individuals with other serious eye conditions, those who can't tolerate the imaging process, or those who are pregnant won't be able to join. Participants can expect to undergo retinal imaging, and their involvement will help researchers learn more about these eye diseases, ultimately aiming to improve diagnosis and treatment options in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Male or female participants 18 years of age or older who have full legal capacity to volunteer on the date the informed consent is signed.
• • 2. Participants who understand the study and patient information sheet and can follow the instructions.
• • 3. Participants who agree to participate in the study.
• • 4. Control group where no retinal abnormalities were detected as part of the standard basic ophthalmic examination.
• • 5. Participants with retinal disease in at least one eye including: Early dry age-related macular degeneration, late stage dry age-related macular degeneration specifically geographic atrophy, Wet age-related macular degeneration, Retinitis pigmentosa, Diabetic retinopathy and other macular atrophic diseases
• Exclusion Criteria:
• • 1. Inability to understand written and verbal English sufficiently to comprehend the study and provide informed consent
• • 2. Ophthalmic disease other than condition under investigation.
• • 3. Participants unable to tolerate ophthalmic imaging.
• • 4. Cataract (unless deemed mild in the opinion of the investigator)
• • 5. Participants with significant ocular media not sufficiently clear to obtain acceptable OCT images.
• • 6. Diabetes (unless part of the diabetic eye disease group)
• • 7. Binocular visual acuity worse than 6/18
• • 8. Strabismus (squint)
• • 9. Age related macular degeneration groups: polypoidal choroidal vasculopathy
• • 10. Participants with photo sensitivity epilepsy, experience of seizures, or sensitivity to flickering light (based on self-report)
• • 11. Pregnant