Improving Genomic Profiling and Reducing Time to Cancer Treatment Via Targeted Use of Endoscopic Ultrasound
Launched by ZEALAND UNIVERSITY HOSPITAL · Feb 21, 2025
Trial Information
Current as of July 24, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Overall aim:
To investigate whether the novel FNB needle provides a better diagnostic accuracy than a standard FNA needle in EUS-B guided cancer diagnosis.
Design:
Prospective multicenter randomized control superiority study.
Primary study objective:
Comparing the ability to provide comprehensive phenotyping from microscopy histology/cytology to the molecular level to allow for optimal and early personalized cancer-specific therapy of FNA and FNB from tumors and lymph nodes adjacent to the esophagus/stomach using EUS-B in patients referred with suspected cancer.
The main focus are com...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Suspicion of lung cancer or lymphoma based on chest CT or PET-CT
- • Lesions adjacent to the esophagus/stomach (e.g. lung tumor, enlarged/FDG-avid lymph nodes in mediastinum or retroperitoneum, left liver lobe metastasis)
- Exclusion Criteria:
- • Other previous cancer with CT or PET-CT suggesting recurrence (e.g. pulmonary metastasis)
- • Uncorrected coagulopathies or anticoagulation treatment that cannot be discontinued
- • Pregnant or lactating women
- • CT suggesting interposed large vessels between the esophagus/stomach and target lesion
About Zealand University Hospital
Zealand University Hospital is a leading academic medical center located in Denmark, dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital leverages its extensive expertise in various medical fields to improve patient outcomes and enhance treatment methodologies. With a commitment to rigorous scientific standards and ethical practices, Zealand University Hospital collaborates with multidisciplinary teams to explore new therapies and interventions, contributing significantly to the global body of medical knowledge. Through its state-of-the-art facilities and focus on patient-centered care, the hospital plays a pivotal role in shaping the future of medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Næstved, , Denmark
Odense, , Denmark
Roskilde, , Denmark
Patients applied
Trial Officials
Uffe Bodtger, MD, PhD
Principal Investigator
Department of Medicine, Zealand University Hospital, Roskilde, Denmark
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported