Tubeless Surgery With Impaired Pulmonary Function

Launched by THE SECOND HOSPITAL OF SHANDONG UNIVERSITY · Feb 22, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new approach to surgery for patients with decreased lung function. Traditionally, after surgery, many patients need to be put on a breathing machine with a tube to help them breathe, which can sometimes lead to complications like airway injury and respiratory failure. The trial is looking at a method called "tubeless surgery," where patients remain awake and breathe on their own during the procedure. This could help reduce the risks associated with using a breathing machine and might allow more patients with weakened lung function to have minimally invasive surgeries safely.

To be eligible for the trial, patients should have reduced lung function and may need surgery for conditions like lung cancer or lung tumors. They should be mentally alert and able to participate in their care. If they choose to join the trial, participants can expect to undergo a minimally invasive surgery without the need for a breathing tube, and the study aims to assess how safe and effective this method is, as well as when it’s appropriate to monitor them after surgery. This trial is currently recruiting patients of various ages and both genders who meet the criteria.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with impaired lung function (who may require postoperative intubation and transfer to the surgical ICU after preoperative and MDT discussions).
• • 2. Patients requiring minimally invasive lung resection due to lung cancer, pulmonary nodules, benign lung tumors, pneumothorax, lung volume reduction surgery, etc.
• • 3. Patients with normal mental status who can cooperate with perioperative examinations, exercises, and physical rehabilitation measures.
• • 4. Patients who agree to participate in the clinical trial after communication.
• Exclusion Criteria:
• • 1. Patients with severe impairment of cardiopulmonary function or other organ systems, who are deemed unable to tolerate any form of anesthesia or minimally invasive surgery after preoperative and MDT discussions.
• • 2. Patients with abnormal mental status or who are unable to adequately cooperate with perioperative examinations, exercises, and physical rehabilitation measures.
• • 3. Patients who refuse to participate in the clinical trial or decline the use of non-intubated anesthesia with preserved spontaneous breathing.
• • 4. Patients who refuse to undergo surgery.