Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus Surgery

Launched by AIN SHAMS UNIVERSITY · Feb 22, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two medications, lidocaine and dexmedetomidine, on reducing bleeding during a specific type of surgery called functional endoscopic sinus surgery (FESS). The goal is to see which medication works better for managing bleeding during the procedure.

To be eligible to participate in this trial, you need to be between 18 and 65 years old and scheduled for an elective FESS. However, some health conditions may prevent participation, such as diabetes, bleeding disorders, or heart problems. If you join the study, you'll receive either lidocaine or dexmedetomidine during your surgery, and researchers will monitor how well each medication helps control bleeding. This trial is currently looking for participants, and it aims to improve surgical outcomes for patients undergoing this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age from 18 to 65 years old.
• • American Society of Anesthesiologists (ASA) physical status I - II.
• • Scheduled for elective functional endoscopic sinus surgery.
• Exclusion Criteria:
• • Diabetes mellitus.
• • Coagulation disorders.
• • Kidney and liver dysfunction.
• • Cerebrovascular disease.
• • Cardiovascular problems.
• • High blood pressure.
• • Asthma.
• • Chronic obstructive pulmonary disease (COPD).
• • End organ damage.
• • Psychosis.
• • Taking antipsychotic drugs.
• • Allergy to study drugs.
• • Substance abuse.
• • Taking beta blockers.
• • Heart rate of \< 55 beat/minute.