Corneal Endothelial Assessment After Posterior Chamber Phakic Intraocular Lens Implantation

Launched by SOHAG UNIVERSITY · Feb 26, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a specific eye surgery called phakic intraocular lens (IOL) implantation on the health of the cornea, which is the clear front part of the eye. The researchers want to determine how this surgery affects the corneal endothelial cells, which are important for maintaining clear vision. To evaluate these effects, they will use a special camera called a specular microscope to take detailed pictures of the cornea before and after the surgery.

The trial is currently looking for participants who are healthy adults between the ages of 18 and 35, have significant nearsightedness (myopia) of more than 6 diopters, and meet certain eye health criteria. Participants should have a stable eye prescription for at least a year and a specific measurement of their corneal endothelial cells. People with certain eye or health conditions, previous eye surgeries, or who are pregnant or nursing will not be eligible. If you decide to participate, you can expect regular assessments of your eye health throughout the study to help researchers understand the impact of this surgery on your cornea.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Our inclusion criteria include: adults 18-35 years of age, myopia ˃ 6 D , anterior chamber depth (ACD) 2.85 mm or greater , an endothelial cell count of ≥ 2000 cells/mm2 and stable refractive history within 0.5 diopter for 1 year.
• Exclusion Criteria:
• • anterior chamber depth from endothelium \< 2.85 mm, previous or current systemic or eye disease , surgery or trauma, pregnancy and nursing.