Investigation of the Relationship Between Central Sensitization and Balance in Fibromyalgia

Launched by SULTAN ABDULHAMID HAN TRAINING AND RESEARCH HOSPITAL, ISTANBUL, TURKEY · Feb 24, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how certain factors related to central sensitization—where the nervous system becomes overly sensitive—affect balance in women with fibromyalgia. The researchers want to understand if these sensitivity factors are different in women with fibromyalgia compared to healthy women and how they may impact balance when standing still (static balance) and when moving (dynamic balance).

To participate in this study, women aged 18 to 65 who have been diagnosed with fibromyalgia can apply. Participants will be asked to give their consent to join the study and will likely undergo balance tests and assessments related to their condition. It's important to know that some individuals, such as those with certain medical conditions or recent surgeries, may not be eligible to participate. This study aims to provide insights that could help improve balance and overall quality of life for those living with fibromyalgia.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of FMS according to the ACR 2016 diagnostic criteria
• • Being between the ages of 18 and 65
• • Being literate
• • Providing informed consent by signing the voluntary consent form
• Exclusion Criteria:
• • Being under 18 years old or over 65 years old
• • Presence of vestibular disorders
• • Having undergone spinal and/or extremity surgery (such as for back/hip/knee/foot) within the last 6 months
• • History of lower extremity amputation
• • Presence of spinal deformities
• • Peripheral arterial disease
• • Vitamin B12 deficiency
• • Any neurological disorder (e.g., stroke, traumatic brain injury, multiple sclerosis, Parkinson's disease, central nervous system malignancies, etc.)
• • Severe cardiopulmonary insufficiency (stage 3-4)
• • Uncontrolled systemic diseases such as hypertension and diabetes
• • Presence of systemic inflammatory diseases, malignancies, or active infections
• • Pregnancy