Comparing Thoracolumbar Interfascial and Quadro Iliac Plane Blocks on Postoperative Opioid Use Following Lumbar Microsurgery

Launched by MEDIPOL UNIVERSITY · Feb 24, 2025

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ClinConnect Summary

This clinical trial is studying two different ways to manage pain after a common back surgery called lumbar microdiscectomy, which is often done to treat herniated discs. Researchers want to see how well two types of nerve blocks, the Thoracolumbar Interfascial Plane (TLIP) block and the Quadro Iliac Plane block, can help reduce the need for opioid pain medications after surgery. Opioids can be effective for pain relief but may cause unwanted side effects like nausea, difficulty breathing, and dependency. By comparing these two methods, the study aims to determine which one leads to less opioid use and fewer side effects.

To participate in this trial, individuals should be between the ages of 18 and 80 and scheduled for lumbar microdiscectomy surgery. They should be in good health overall, classified as ASA physical status I to III, which means they have no serious health issues. However, people with certain allergies, those who are pregnant, or anyone with significant mental health or neurological conditions cannot join the study. Participants will receive either of the two nerve blocks before their surgery and will be monitored afterward for pain levels and any side effects, helping to improve pain management practices for future patients.

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Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 to 80 years
• • American Society of Anesthesiologists (ASA) physical status I to III
• • scheduled for lumbar microdiscectomy surgery
• Exclusion Criteria:
• • Known allergy to local anesthetics
• • Any other significant drug allergies related to the study interventions
• • Pregnancy
• • Pre-existing psychiatric or neurological disorders
• • Inability to provide informed consent