Nutrition-based Interventions to Prevent Cognitive Decline

Launched by INSTITUTO DE SAUDE PUBLICA DA UNIVERSIDADE DO PORTO · Feb 27, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on finding out if nutrition-based programs can help prevent cognitive decline, which includes issues like memory loss and other thinking problems. The study will involve group sessions where participants learn about nutrition and physical activity, as well as personalized training they can do at home. The goal is to address factors that can be changed to reduce the risk of developing dementia, all while considering what participants prefer in their nutrition-related activities.

To be eligible for this study, participants need to be between 55 and 85 years old, have completed at least four years of schooling, and have a higher risk for dementia based on a specific scoring system. However, those who already have significant cognitive impairment, certain medical conditions that affect their ability to participate, or a diagnosis of dementia won’t be eligible. Participants can expect to engage in both group and individual sessions that focus on nutrition and healthy living, which may help support their cognitive health. The trial is currently recruiting participants, and it welcomes individuals of all genders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged from 55 to 85 years old;
• • At least 4 years in the regular school system;
• • Higher individual risk for dementia defined as a score ≥6 points on the Cardiovascular Risk Factors, Aging and Dementia Dementia Risk Score (CAIDE).
• Exclusion Criteria:
• • Montreal Cognitive Assessment (MoCA) score lower than the validated cutoff points defined as 2 standard deviations below the normative reference value for the corresponding age and education in the Portuguese population;
• • Having a medical condition limiting the participation in the intervention (e.g., blindness, amputation...);
• • Lack of autonomy in daily activities;
• • Diagnosis of dementia or major incapacity.