Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study
Launched by EGE UNIVERSITY · Feb 25, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at different treatments for dentin hypersensitivity, which is a common problem where teeth feel painful or sensitive to hot, cold, or sweet things. Researchers want to find out if using special toothpastes, desensitizing agents, and a specific type of laser treatment can help reduce this sensitivity. They will also check to see if these treatments cause any side effects.
To participate in the study, you need to be at least 18 years old, have good oral hygiene, and experience sensitivity in at least three teeth. If you join, you will be placed in one of four groups and receive two treatment sessions, one week apart. After that, you’ll have follow-up visits to check how well the treatments are working. This study is not yet recruiting participants, but it aims to find the best way to manage dentin hypersensitivity effectively and safely.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Individuals over the age of 18,
- • 2. Individuals with good oral hygiene,
- • 3. Individuals without systemic contraindications for treatment,
- • 4. Individuals who are reliable for periodic follow-ups, cooperative, and willing to participate in the study,
- • 5. Individuals with sensitivity in at least three teeth,
- • 6. Individuals who have been using a standard toothpaste containing 1100 ppm fluoride for at least one month.
- Exclusion Criteria:
- • 1. Individuals with a history of alcohol, drug, or medication addiction,
- • 2. Individuals known to be unable to attend follow-up sessions,
- • 3. Individuals with allergies to any of the products used in the study,
- • 4. Individuals with unstable mental or physical conditions,
- • 5. Pregnant or breastfeeding individuals, as well as those planning pregnancy during the study.
About Ege University
Ege University, a prestigious institution located in Izmir, Turkey, is renowned for its commitment to advancing medical research and education. As a prominent clinical trial sponsor, Ege University leverages its extensive academic resources and expertise in various healthcare fields to facilitate innovative clinical studies. The university is dedicated to enhancing patient care through rigorous research methodologies and collaboration with multidisciplinary teams, ensuring the development of effective therapies and interventions. With a strong focus on ethical standards and regulatory compliance, Ege University aims to contribute significantly to the global medical community by fostering groundbreaking discoveries and improving health outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported