Zinc Oxide Ozonated Olive Oil in LSTR

Launched by TANTA UNIVERSITY · Feb 25, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment called zinc oxide-ozonated olive oil (ZnO-OO) compared to a standard treatment known as Modified Triple Antibiotic Paste (MTAP) for children with a specific dental issue called pulpitis, which is an infection inside a tooth. The goal is to see which treatment works better for helping heal primary molars (the back teeth in children) that are infected or damaged.

To participate in this study, children aged 4 to 7 years old who are healthy enough to cooperate will be eligible, especially if they have certain signs of tooth infection, like pain or tenderness. The trial is focused on teeth that can still be repaired, so teeth that are too damaged will not qualify. If your child is chosen to take part, they will receive one of the two treatments, and the researchers will monitor their progress. This is a great opportunity to help improve dental care for kids in the future!

Gender

ALL

Eligibility criteria

• • Inclusion Criteria: 1- Cooperative patients in the age group of (4-7) years with no associated systemic illness.
• • 2- Bilateral mandibular primary molars showing signs and symptoms of pulp necrosis or chronic pulp infection with/without hemorrhage, suppuration, or purulence.
• 3- Spontaneous pain or tenderness to percussion. 4- Presence of chronic apical abscess, sinus tract, or grade I mobility. 5-The tooth should be restorable. 6- Radiographic characteristics are:
• • 1. Widening of Periodontal ligament space.
• • 2. Radicular involvement.
• • 3. Furcation involvement less than or equal to half of the shortest root in the vertical dimension
• • -
• Exclusion Criteria: Exclusion criteria :
• • 1. Physiologic root resorption is more than one-third of its length.
• • 2. Excessive internal resorption.
• • 3. Non-restorable teeth exhibiting greater than grade I mobility.
• • 4. Perforation into the bifurcation.
• • 5. Any underlying pathological lesion.
• • 6. Any previous history of allergy to the antibiotics used in the study. -