Cohort of Patients With Systemic Granulomatosis and Associated Biological Collection

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Feb 25, 2025

Keywords

ClinConnect Summary

The GRAMI-BIO study is a research project aimed at understanding systemic granulomatosis, a condition that causes inflammation in various parts of the body. Over the next ten years, researchers at Bordeaux University Hospital will recruit 150 patients who have been diagnosed with this condition. The study will not only look at how the disease progresses in these patients but also collect different types of biological samples, like blood and urine, to help with future research.

To be eligible for this study, participants must be at least 18 years old and have a confirmed diagnosis of systemic granulomatosis. They also need to be part of a social security program and provide written consent to join. However, individuals who are pregnant, have certain viral infections, or are already undergoing specific treatments for granulomatosis will not be able to participate. If you decide to join, you will be followed for five years after your initial enrollment, and you can expect regular check-ups to monitor your condition and collect the necessary samples.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 or over
• • Patients with systemic granulomatosis (diagnosis proven by anatomopathological sampling) at diagnosis.
• • Persons affiliated to or benefiting from a social security scheme.
• • Free, informed and written consent signed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research).
• Exclusion Criteria:
• • Patients infected with human immunodeficiency virus (HIV), Hepatitis B virus (HBV) and/or Hepatitis C virus (HCV)
• • Pregnant or breast-feeding women
• • Patients already receiving specific treatment for systemic granulomatosis
• • Persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent.