NoPro - Norwegian Hernia Prophylaxis Study

Launched by SYKEHUSET INNLANDET HF · Feb 28, 2025

Keywords

ClinConnect Summary

The NoPro study is a clinical trial designed to learn more about preventing incisional hernias, which can occur after surgery involving a midline incision in the abdomen. Researchers are comparing two methods of closing the incision: one using a small-bite suture technique alone, and the other using the same technique but with an additional layer of protective mesh. The main goal is to see how many patients develop an incisional hernia within one year after their surgery.

You may be eligible to participate in this trial if you are at least 18 years old and are scheduled for surgery that involves a midline incision with delayed closure. It’s important to note that the study is open to all genders, and participants must provide written consent. If you join the study, you’ll be randomly assigned to one of the two closing methods, and researchers will monitor your recovery and any complications over the year. This research could help improve surgical care and quality of life for future patients undergoing similar procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Surgery predominantly done my midline laparotomy
• • Age 18 years old or older
• • Written consent by patient/family
• • Midline laparotomy with delayed closure
• • No exclusion criteria
• Exclusion Criteria:
• • Age under 18 years
• • Pregnancy
• • Previous abdominal midline hernia mesh repair
• • Abdominal compartment syndrome
• • Linea alba closure not possible
• • Life expectancy under six months
• • Hernia in the midline with transverse diameter lager than 2 cm