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Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

Launched by UNIVERSITY OF PENNSYLVANIA · Feb 27, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Social Skills Emotion Regulation Autistic Adults

ClinConnect Summary

This clinical trial is studying a new program called TUNE In, which aims to help adults with Autism Spectrum Disorder (ASD) improve their social skills and interactions. The program focuses on different areas that affect how people with autism communicate and connect with others, such as understanding emotions, overcoming social anxiety, and applying skills in everyday situations. Researchers want to see if TUNE In can make a positive difference in social functioning for adults with ASD.

To participate in the trial, individuals need to be at least 18 years old, have a confirmed diagnosis of autism, and score 60 or higher on a specific social responsiveness survey. However, people with severe behavioral issues or certain recent mental health challenges are not eligible. Those who join the study will complete surveys to help measure their progress. This trial is currently recruiting participants and aims to provide valuable insights into effective strategies for enhancing social skills in adults with autism.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18 years of age or older
  • Meet ASD diagnostic criteria supported by an outside diagnostic evaluation and/or by the clinical and developmental information gathered from a phone screen
  • Be willing to complete screening surveys (outcome measures)
  • Social Responsiveness Score, Second Edition, self-report SRS survey score of greater than or equal to 60
  • Exclusion Criteria:
  • Severe self-injurious or aggressive behaviors; or with suicidal or homicidal ideation or behaviors (e.g. suicide attempt) within the last 6 months
  • Major mood episode (major depressive episode, manic episode), psychotic symptoms, or a psychiatric hospitalization within the last 6 months
  • A history of intellectual disability or low Shipley-2 score

About University Of Pennsylvania

The University of Pennsylvania, a prestigious Ivy League institution located in Philadelphia, is renowned for its commitment to advancing medical research and improving healthcare outcomes. As a clinical trial sponsor, the university leverages its extensive resources, interdisciplinary expertise, and cutting-edge facilities to conduct innovative studies across various therapeutic areas. With a focus on translating scientific discoveries into clinical applications, the University of Pennsylvania fosters collaborations among leading researchers, clinicians, and industry partners, ensuring rigorous trial design and adherence to ethical standards. Through its dedication to excellence in research and education, the university plays a pivotal role in shaping the future of medicine.

Locations

Philadelphia, Pennsylvania, United States

Patients applied

0 patients applied

Trial Officials

Edward Brodkin, MD

Principal Investigator

University of Pennsylvania

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported