Prospective Randomized Non-Inferiority Study Comparing Natural Cycle Frozen Embryo Transfer (NC-FET) to a New Type of Endometrial Preparation for FET: Natural Proliferative Phase (NPP-FET)

Launched by ERASME UNIVERSITY HOSPITAL · Mar 4, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different methods for transferring frozen embryos to see which one might be better for achieving pregnancy. The two methods being compared are called Natural Cycle Frozen Embryo Transfer (NC-FET) and a newer approach called Natural Proliferative Phase Frozen Embryo Transfer (NPP-FET). The goal is to find out if NPP-FET is just as effective as the traditional method, while also offering better planning options for patients.

Women between the ages of 18 and 40 who are considering a single embryo transfer may be eligible to participate. Participants will be randomly assigned to one of the two methods and monitored for pregnancy success, which is measured by checking hormone levels after the embryo transfer. This trial is currently recruiting, so if you or someone you know fits the criteria, it could be an opportunity to explore new options in fertility treatment.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Single transfer Blastocyste
• Exclusion Criteria:
• • PGT (Preimplantation genetic diagnosis)
• • Testicular Sperm
• • Donor oocytes