Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

Launched by UNC LINEBERGER COMPREHENSIVE CANCER CENTER · Feb 28, 2025

Keywords

ClinConnect Summary

This clinical trial, titled "Combating Cancer-Related Fatigue: A Personalized Supportive Care Program," is designed to help patients with certain types of indolent lymphomas, including chronic lymphocytic leukemia and follicular lymphoma, who are experiencing significant fatigue. The study will involve a total of 40 participants, and its goal is to evaluate a specialized program that aims to reduce fatigue through various supportive care strategies. The trial is not yet recruiting, but it will focus on individuals aged 18 and older who have been diagnosed with these conditions and have a high level of fatigue.

To be eligible for the study, participants must provide written consent and agree to follow study procedures. They should have a confirmed diagnosis of indolent lymphoma and report significant fatigue, as measured by a specific scoring system. Individuals with other serious health issues, cognitive impairments that could affect their understanding of the study, or those unable to eat solid food will not be able to join. If you or a loved one meets these criteria and is interested in participating, you can expect to take part in a supportive care program aimed at improving energy levels and overall well-being.

Gender

ALL

Eligibility criteria

• • In order to participate in this study a subject must meet all of the eligibility criteria outlined below.
• Inclusion Criteria:
• • Written informed consent was obtained to participate in the study and HIPAA authorization for the release of personal health information.
• • Subjects are willing and able to comply with study procedures based on the judgment of the investigator.
• • Age ≥ 18 years at the time of consent.
• • Confirmed diagnosis of indolent lymphoma, Waldenström's Macroglobulinemia, or Cutaneous T Cell Lymphoma.
• • Significant symptoms of fatigue, as defined by PROMIS Fatigue score \>50.
• Exclusion Criteria:
• • Other co-existing malignancies.
• • Significant cognitive impairment as defined by Mini-Cog score 0-2 (out of 5) that would prevent understanding of assessments or interventions.
• • Unstable or serious illness (e.g., unstable cardiac arrhythmia, severe anemia/thrombocytopenia) that would prevent safe participation in an exercise regimen, per the discretion of the treating physician.
• • Individuals who are not able to consume an oral diet, due to swallowing difficulties or other reasons, as this might interfere with the nutritional intervention