Effect of Positive End-expiratory Pressure on the Gastric Volume

Launched by SEOUL NATIONAL UNIVERSITY BUNDANG HOSPITAL · Mar 2, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how a technique called Positive End-expiratory Pressure (PEEP) affects the amount of air and fluids in the stomach during certain types of surgery, particularly for women with breast cancer. The goal is to understand if using PEEP while a special breathing device (known as a supraglottic airway device) helps or harms the stomach's condition. By gathering this information, the researchers hope to improve the safety and management of patients undergoing anesthesia.

To participate in this study, you need to be an adult aged 19 or older who is scheduled for elective surgery under general anesthesia. You should be in good health according to certain medical guidelines. However, if you have conditions that might complicate the use of the breathing device or PEEP, such as obesity, certain respiratory diseases, or a history of gastrointestinal surgery, you may not be eligible. If you join the trial, you can expect to help researchers gather valuable information that could lead to better care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients aged 19 and above.
• • Patients scheduled for general anesthesia for elective surgery.
• • American society of anesthesiologists physical status classification 1 or 2
• Exclusion Criteria:
• • Individuals who have not provided prior consent for participation in the study
• • Patients showing cognitive impairment to the extent that voluntary consent is difficult
• • Obesity with a BMI of 30 kg/m² or higher
• • Patients with anatomical abnormalities in the airway structure making supraglottic airway device application difficult
• • Patients with respiratory diseases making PEEP application difficult (e.g., chronic obstructive pulmonary disease, asthma)
• • Patients suspected of delayed gastric emptying (e.g., not adhering to fasting guidelines, medication use affecting gastric motility \[anticholinergics, narcotic analgesics\], neurological disorders \[Parkinson's disease, multiple sclerosis\], diabetes, hypothyroidism)
• • Patients with a history of gastrointestinal surgery
• • Pregnant women
• • Patients undergoing concurrent surgeries or collaborative procedures
• • Patients transferred from the intensive care unit