Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)

Launched by UNIVERSITY OF SAO PAULO · Feb 28, 2025

Keywords

ClinConnect Summary

This clinical trial, called POC Troponina, is studying two different ways to measure a heart-related protein called troponin I, which helps doctors determine if someone is having a heart attack. The goal is to find out if using a quick test, done right in the emergency room, can help patients leave the hospital sooner compared to the standard lab test that takes longer. Researchers will compare how quickly they can make decisions about treatment and how accurate the results are with both methods.

To be eligible for this trial, participants need to be at least 18 years old and must arrive at the emergency room with chest pain that started between 3 to 12 hours before coming in. They also need to agree to participate by signing a consent form. However, people who have certain heart conditions, serious illnesses like kidney disease or cancer, or who are pregnant or breastfeeding cannot take part. If you join the study, you can expect to have your troponin levels tested using both methods, and the researchers will monitor how this affects your hospital stay.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged ≥ 18 years.
• • Patients arriving in the emergency room with symptoms suggestive of ACS, with onset of pain between 3 and 12 hours after arrival, in whom serial troponin dosing is planned for investigation.
• • Signature of the Informed Consent Form (ICF).
• Exclusion Criteria:
• • Patients presenting with ACS with ST-segment elevation on the 12-lead ECG on arrival at hospital.
• • Patients with conditions that interfere with the interpretation of troponin dosage (chronic renal failure, cancer, chronic lung diseases).
• • Pregnant or breastfeeding patients.
• • Patients already included in other clinical research protocols.