The Correlation Between Intraoperative End Tidal Carbon Dioxide, Perfusion Index and Pulse Variability Index on Postoperative Nausea Vomiting and Pain
Launched by NAIME YALÇIN · Mar 5, 2025
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
In recent years, laparoscopic gynecologic surgery has become a preferred technique over traditional open surgery due to its benefits such as better cosmetic results, lower risk of bleeding, minimally invasive surgery, lower postoperative pain and incidence of wound infection, and as a result, earlier discharge.
PI (Perfusion index), the ratio of alternating current component to direct current component, is a representation of the photoplethysmography waveform that quantitatively reflects real-time changes in peripheral blood flow in the monitored region. PVI (Pulse variability index) is an...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Planned for elective total laparoscopic hysterectomy
- • 20-65 years old
- • ASA I - II
- Exclusion Criteria:
- • history of intracranial disease
- • lung disease
- • systemic hypertension
- • ischemic heart disease
- • history of postoperative nausea and vomiting in previous operations
- • smoking habit
- • motion sickness
- • liver and kidney dysfunction
- • abnormal fluid-electrolyte balance
- • preoperative use of antiemetic drugs
- • severe heart failure
- • ASA III and above
- • body mass index\> 35 kg m2
About Naime Yalçın
Naime Yalçın is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes. With a strong focus on innovative therapeutic solutions, Naime Yalçın oversees the planning, execution, and management of clinical trials across various therapeutic areas. The organization prioritizes regulatory compliance, ethical standards, and the integrity of data, ensuring that all trial activities are conducted with the utmost professionalism. Through collaboration with healthcare professionals and research institutions, Naime Yalçın aims to facilitate the development of safe and effective treatments that meet the needs of patients and contribute to the broader medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
İstanbul, , Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported