Vestibulodynia At High Resolution: Omics Approach to Improve Diagnosis

Launched by FONDAZIONE IRCCS POLICLINICO SAN MATTEO DI PAVIA · Mar 6, 2025

Keywords

ClinConnect Summary

This clinical trial is studying vestibulodynia (VBD), a common condition that causes pain in the vaginal area without a clear cause. The goal is to find better ways to diagnose VBD by examining the cells in the vestibular region of women who experience this pain. Researchers believe that understanding the biological differences in this area could lead to the development of specific tests that help identify VBD earlier, which is crucial since many women suffer in silence due to lack of awareness and understanding of this condition.

To participate, women aged 18 to 50 who have not engaged in sexual intercourse or used intravaginal products for a week prior to the visit may be eligible. Those with other conditions, such as generalized vulvodynia, endometriosis, or recent infections, are excluded. Participants can expect a pain-free cell swab test from the vaginal area, which will help researchers look for specific markers of VBD. This could lead to improved diagnosis and personalized treatment options for women suffering from this condition, ultimately aiming to enhance their quality of life.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age between 18 and 50
• • abstinence from intercourse for 7 days prior to the visit
• • non-use of intravaginal products for 7 days prior to the visit
• Exclusion Criteria:
• • patients whit generalized vulvodynia and those with only spontaneous, but not provoked vestibulodynia
• • Endometriosis
• • Pregnancy
• • Infectious vulvar disease
• • Post-menopause
• • Feeding time
• • gave birth within 4 months
• • received systemic or vaginal antimicrobial or probiotic therapy within 1 month before the visit