Laparoscopic Versus Transvaginal Closure of the Vaginal Vault After Total Laparoscopic Hysterectomy
Launched by AIN SHAMS UNIVERSITY · Mar 4, 2025
Trial Information
Current as of September 08, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking to compare two different methods for closing the vaginal vault after a total laparoscopic hysterectomy (TLH), which is a surgery to remove the uterus. The two methods being studied are laparoscopic closure (done through small incisions) and transvaginal closure (done through the vagina). The main goal is to see which method has a lower risk of complications, such as bleeding, infections, and issues with sexual function.
To participate in this trial, you need to be an adult female who is planning to have a TLH for non-cancerous conditions and is in a healthy weight range. You should also be sexually active. However, if you have certain health issues, such as obesity, cancer, or conditions that affect healing, you may not be eligible. If you choose to participate, you can expect to receive either of the two closure techniques and be monitored for any complications after your surgery. This trial is still recruiting participants, so there’s an opportunity to contribute to important research that may help improve surgical outcomes for women.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Adult females consenting to do TLH all age groups with diagnoses of benign uterine conditions.
- • Women who are non-obese (normal or overweight women with BMI range 18-29.9).
- • Sexually active female.
- Exclusion Criteria:
- • Diagnosed cases of pelvic malignancy
- • Diagnosed patients with Cervical intraepithelial neoplasia (CIN) or bacterial vaginosis (any infection should be treated)
- • Obese patients.
- • Patients currently undergoing treatment for any type of cancer
- • Patients with coagulopathy, bleeding/clotting disorders
- • Patients with any condition can impair wound healing: diabetes mellites, anemia, steroids
- • Patients with a previous history of radiation and allergy to sutures
- • Patients with clinically evident prolapse
About Ain Shams University
Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported