Comparing Closed Face Masks vs Surface Guided Radiation Therapy for Head and Neck Radiotherapy

Launched by UNIVERSITY OF ZURICH · Mar 5, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at the comfort and effectiveness of two different types of masks used during radiation therapy for patients with head and neck cancers. Currently, many patients wear closed face masks, which can feel uncomfortable, while some patients with anxiety use open face masks. This trial aims to compare the use of closed face masks with no masks at all to see which option helps patients feel more comfortable and allows for better setup accuracy during treatment.

To participate in this trial, you need to be at least 18 years old and have a doctor’s recommendation for head and neck radiation therapy. You should also be able to follow the study's procedures and attend scheduled visits. However, if you have previously received radiation to your head or neck, are pregnant or breastfeeding, or have other specific health concerns, you may not be eligible. Participants will be asked to provide written consent and will be closely monitored throughout the study to ensure their safety and comfort. This trial is not yet recruiting participants, but it aims to improve the experience of patients undergoing this important treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Written informed consent according to Swiss law and ICH/GCP regulations before any trial specific procedures;
• • Indication for head and neck radiotherapy irrespective of tumor type;
• • Age: ≥ 18 years old;
• • Karnofsky performance status ≥70;
• • Patients who are willing and able to comply with scheduled visits, treatment, and other trial procedures.
• Exclusion Criteria:
• • Prior head and neck irradiation;
• • Women who are pregnant or breast feeding;
• • Intention to become pregnant during the course of the trial;
• • Lack of safe contraception, defined as: Female participants of childbearing potential, not using and not willing to continue using a medically reliable method of contraception for the entire study duration, such as oral, injectable, or implantable contraceptives, or intrauterine contraceptive devices, or who are not using any other method considered sufficiently reliable by the investigator in individual cases;
• • Known or suspected non-compliance, drug or alcohol abuse;
• • Inability to follow the procedures of the trial, e.g. due to language problems of the participant;
• • Enrolment of the investigator, his/her family members, employees and other dependent persons.
• • One of the following Tumor Types: Nasopharynx, Sinunasal, patients with CTV within 5 mm of eyes or spinal cord.