Impact of Sarcopenia on Dyspnea in Patients With Asthma

Launched by UNIVERSITY HOSPITAL, CLERMONT-FERRAND · Mar 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how sarcopenia, which means loss of muscle mass and strength, affects breathing difficulties (called dyspnea) in patients with asthma. While asthma is often linked to problems in the airways, researchers want to learn more about how sarcopenia might make these breathing issues worse. By understanding the connection between muscle health and asthma, the goal is to improve treatment and care for patients who have both conditions.

To participate in the trial, individuals must be at least 18 years old and have a specific type of asthma that requires advanced treatment. They should also have a score indicating poor asthma control. Participants will need to be able to perform a maximal exercise test, which helps assess their fitness level. Notably, those who are pregnant, have unstable heart conditions, or have recently smoked are not eligible to join. The trial is not yet recruiting participants, but it aims to gather important information that could lead to better management of asthma and sarcopenia in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Patient affiliated to a social security scheme.
• • Patient capable of giving free, informed, written and signed consent.
• • Asthmatic patients with a diagnosis made by a pulmonologist on GINA level 4 or 5 treatment
• • ACT asthma control score \< 20
• • Patient judged by the investigator to be able to to perform a maximal exercise test.
• Exclusion Criteria:
• • Patient under guardianship/trusteeship/supervision of justice
• • Pregnant or breast-feeding women
• • Unstable heart disease
• • Patients who have been smoking or have stopped smoking for less than 5 years,