Evaluating the Impact of a Functional and Cognitive Strategy in Patients with Long Covid-19

Launched by FUNDACIÓN CARDIOINFANTIL INSTITUTO DE CARDIOLOGÍA · Mar 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how a special rehabilitation program can help people with Long COVID-19, especially those who also have other chronic health issues like high blood pressure or diabetes. The researchers want to see if participating in a structured program that includes physical and mental exercises can improve patients' daily functioning, thinking abilities, and overall quality of life compared to just receiving helpful information about their condition.

To participate, individuals must have had a confirmed COVID-19 infection and be experiencing ongoing symptoms, like fatigue or difficulty breathing, that affect their daily life for at least four weeks. Eligible participants will be randomly placed into one of two groups: one will attend weekly sessions with exercises for eight weeks, while the other will receive educational messages. Throughout the study, participants will take part in various assessments to measure their progress. It's important to note that this trial is not yet recruiting participants, and certain health conditions may prevent some individuals from joining.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Covid-19 confirmed.
• • History of arterial hypertension or diabetes mellitus before entering the institutional registries of the FCI-IC or HOMIL, institutional registries of the FCI-IC or HOMIL or before having the diagnosis of SARSCoV-2 infection.
• • Persistence of two or more concurrent symptoms, related to Covid-19 prologue, for at least 4 weeks (persistent, intermittent, or intermittent).
• • At least one of these symptoms must have an impact on activities of daily living. They can be physical (fatigue, dyspnea, myalgias, arthralgias) or neuropsychiatric (cognitive, sleep and emotional alterations).
• • Symptoms unexplained by underlying disease or other condition concomitant with SARS-CoV-2 infection. SARS-CoV-2 infection (determined by prior medical history review and participant interview).
• • participant interview).
• • - Ability to read and attend functional and cognitive rehabilitation sessions or to receive the with evidence-based informational messages.
• Exclusion Criteria:
• • Age \>80 years.
• • Severely advanced baseline comorbidities prior to SARS-CoV-2 infection.
• • Presence of chronic respiratory disease (partial or permanent supplemental oxygen use), cardiac failure (LVEF\<40%) or advanced renal disease (GFR\<30%).
• • heart failure (LVEF\<40%) or advanced renal disease (GFR\<30).
• • Two hospitalizations in the year prior to admission to the institutional registries of the FCI-IC and the HOMIL for the patient's underlying disease.
• • Dependence on a caregiver.
• • Orthopedic or cardiopulmonary problems that contraindicate the performance of aerobic exercise.
• • Neuropsychiatric or cognitive limitations that limit understanding or following commands and performing attention exercises.