Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery

Launched by ISTANBUL UNIVERSITY · Mar 6, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new method to improve bowel surgery for women with gynecologic cancers, like ovarian, endometrial, cervical, or vulvar cancer. The researchers want to see if using a special imaging technique called indocyanine green (ICG) fluorescence can help lower the risk of complications, such as leaks or infections, after surgery. During the operation, a dye will be injected into the bloodstream, and a special camera will help the surgeon check how well blood is flowing at the site where the bowel is reconnected. This information will help the surgeon decide if the connection is safe or if it needs to be adjusted.

To participate in this study, women must be 18 years or older and have a diagnosis of gynecologic cancer that requires surgery involving bowel resection (removing a part of the bowel) and anastomosis (reconnecting the bowel). However, women who are pregnant, breastfeeding, or have a known allergy to ICG, as well as those with serious liver or kidney issues, cannot join. Participants will be monitored for any complications for 30 days after their surgery to find out if this imaging technique can improve surgical outcomes.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female patients aged 18 years or older.
• • Diagnosis of gynecologic cancer (ovarian, endometrial, cervical, vulvar) requiring surgical treatment.
• • Planned bowel resection and anastomosis during gynecologic oncology surgery.
• • Ability and willingness to provide informed consent.
• Exclusion Criteria:
• • Known allergy or hypersensitivity to indocyanine green (ICG).
• • Pregnancy or breastfeeding at the time of surgery.
• • Severe liver or kidney dysfunction limiting the use of ICG.