Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation

Launched by BEIJING ANZHEN HOSPITAL · Mar 6, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how using a device called an Intra-aortic Balloon Pump (IABP) early during treatment can help patients with a serious heart condition known as cardiogenic shock. Specifically, the trial compares this approach to the usual methods used when patients are on a special life-support system called venoarterial extracorporeal membrane oxygenation (VA-ECMO). The main goal is to see if using the IABP can improve health outcomes for these patients.

To participate in this trial, individuals must be at least 18 years old, have cardiogenic shock, and have successfully received VA-ECMO. However, certain conditions, like severe issues with the heart valves or significant bleeding problems, would make someone ineligible. Participants will be randomly assigned to either receive the IABP or follow the standard treatment. This trial is not yet recruiting patients, but it aims to provide valuable information about how to improve care for people with severe heart problems.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age of ≥18
• • 2. Cardiogenic shock
• • 3. Successful implantation of VA-ECMO
• • 4. Informed consent
• Exclusion Criteria:
• • 1. Presence of moderate to severe aortic insufficiency
• • 2. Severe peripheral vascular disease
• • 3. Post-cardiotomy cardiogenic shock or bridging to cardiac procedure.
• • 4. VA-ECMO for definite non-cardiac causes
• • 5. Extracorporeal cardiopulmonary resuscitation
• • 6. Implantation of IABP or IMPELLA before VA-ECMO
• • 7. Severe bleeding
• • 8. Terminal malignancy
• • 9. Irreversible neurologic injury
• • 10. Pregnancy or lactation