Evaluation of the Use of Synthetic Glue for Mesh Fixation in Laparoscopic Sacrocolpopexy

Launched by BRNO UNIVERSITY HOSPITAL · Mar 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new method of fixing a mesh implant during a surgery called laparoscopic sacrocolpopexy, which is a common treatment for a condition known as apical prolapse. The aim is to see if using a special glue, called cyanoacrylate adhesive, can make the surgery faster and safer compared to traditional stitching methods. While laparoscopic sacrocolpopexy is effective, it often takes a long time to perform, which can increase the risk of complications. The researchers want to find out if this glue can shorten the surgery time while still ensuring good results and safety for patients.

To be eligible for this study, participants should be women aged 18 to 75 who have a moderate to severe pelvic organ prolapse. They should also be able to understand Czech and need the surgery for their condition. However, women who want to keep their uterus, those who have already had a hysterectomy, or those with certain health issues related to their reproductive organs cannot participate. If you join the study, you will receive either the new glue method or the traditional stitching method during surgery, and your recovery will be monitored for any complications or discomfort. This trial is important as it is the first of its kind to compare these two techniques directly.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Sufficient knowledge of the Czech language
• • Pelvic organs prolapse of second stage or higher according to POPQ classification (POPQ ≥ 2)
• • Patients indicated for laparoscopic sacropexy - sacrocervicopexy with concomitant supracervical hysterectomy
• Exclusion Criteria:
• • Patients requesting uterine preservation
• • Patients with previous hysterectomy
• • Patients with premalignancy or malignancy of the female reproductive organs
• • Concomitant urethropexy