The Effect of Probiotics on the Improvement of Intestinal and Immune Function

Launched by WECARE PROBIOTICS CO., LTD. · Mar 6, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at whether a specific probiotic, called Lactobacillus delbrueckii subsp. bulgaricus LB42, can help improve intestinal and immune functions in healthy adults. Participants will take this probiotic or a placebo (a non-active substance) daily for a certain period and will be asked to attend three follow-up visits. The trial is not yet recruiting, but it aims to include adults aged 18 to 45 who are in good health and can provide blood, urine, and stool samples during the study.

To be eligible for this trial, participants must not have any serious gastrointestinal or neurological disorders, must not be currently receiving treatment for certain psychiatric conditions, and should not have any major organ failures. During the trial, participants can expect to self-administer the probiotic or placebo and attend follow-up visits for monitoring. The study aims to understand the safety and effectiveness of this probiotic, which could offer insights into improving gut and immune health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18-45 years
• • 2. Willing to undergo 3 follow-up visits during the intervention period
• • 3. Willing to provide 2 blood, urine, and stool samples during the intervention period
• • 4. Willing to self-administer one of the probiotics/placebo once daily during the intervention period
• • 5. Good eyesight, able to read and write, and can wear glasses
• • 6. Have good hearing and be able to hear and understand all instructions during the intervention
• Exclusion Criteria:
• • 1. Suffering from digestive disorders, mainly gastrointestinal disorders (celiac disease, ulcerative colitis, Crohn's disease)
• • 2. Has a severe neurological condition (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, prolonged coma - excluding general anesthesia)
• • 3. Has received/is receiving treatment for the following psychiatric disorders: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder
• • 4. Take medication for depression or low mood
• • 5. Suffering from internal organ failure (heart, liver, or kidney failure, etc.)
• • 6. Radiotherapy or chemotherapy in the past
• • 7. Surgery/procedure under general anesthesia within the past three years, or planned to undergo a procedure/procedure under general anesthesia within the next 3 months during this trial
• • 8. Have had hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past