Oropharyngeal Vs Intravenous Lidocaine Effects on Optic Nerve Sheath Diameter After Intubation
Launched by ANKARA CITY HOSPITAL BILKENT · Mar 8, 2025
Trial Information
Current as of April 30, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different methods of using lidocaine, a numbing medication, affect the optic nerve sheath diameter (ONSD) after a procedure called endotracheal intubation, which is commonly done during surgeries to help patients breathe. The trial will compare two ways of giving lidocaine: one method uses a topical spray in the mouth (oropharyngeal) and the other uses an intravenous (IV) injection. Researchers will measure the ONSD using ultrasound before intubation and at intervals afterward to see how each method affects the optic nerve.
To participate in this trial, you need to be between 18 and 65 years old, have a body mass index (BMI) between 18 and 30, and not have any serious health conditions that could make intubation difficult. You also should not have a history of eye problems or conditions that increase pressure in the brain. If you qualify and choose to participate, you can expect to have some ultrasound measurements taken before and after the intubation. This research aims to help improve patient care during surgeries by understanding the best ways to use lidocaine for numbing.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • ASA class I or II
- • Age 18-65 years
- • BMI 18-30
- • No history or expected difficult intubation
- • No glaucoma or ocular pathology
- • No intracranial pressure increase
- Exclusion Criteria:
- • ASA class III and above
- • Obesity (BMI \> 30)
- • Difficult intubation history or risk
- • Glaucoma or other ophthalmic pathology
- • History of intracranial pressure increase or prior ophthalmic/intracranial surgery
- • Preoperative sedation
- • Active malignancy or ongoing radiotherapy/chemotherapy
About Ankara City Hospital Bilkent
Ankara City Hospital Bilkent is a leading healthcare institution in Turkey, dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. Equipped with state-of-the-art facilities and a multidisciplinary team of experienced professionals, the hospital fosters a collaborative environment for conducting rigorous scientific investigations. Its commitment to ethical standards and patient safety ensures that all clinical trials are conducted with the highest level of integrity, ultimately contributing to the development of new therapies and enhancing the quality of care provided to patients.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, , Turkey
Patients applied
Trial Officials
İsmail Aytaç, Ass. Prof
Principal Investigator
Ankara City Hospital Bilkent
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported