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Search / Trial NCT06874179

Oropharyngeal Vs Intravenous Lidocaine Effects on Optic Nerve Sheath Diameter After Intubation

Launched by ANKARA CITY HOSPITAL BILKENT · Mar 8, 2025

Trial Information

Current as of April 30, 2025

Not yet recruiting

Keywords

Endotracheal Intubation Optic Nerve Sheath Diameter Lidocaine

ClinConnect Summary

This clinical trial is studying how different methods of using lidocaine, a numbing medication, affect the optic nerve sheath diameter (ONSD) after a procedure called endotracheal intubation, which is commonly done during surgeries to help patients breathe. The trial will compare two ways of giving lidocaine: one method uses a topical spray in the mouth (oropharyngeal) and the other uses an intravenous (IV) injection. Researchers will measure the ONSD using ultrasound before intubation and at intervals afterward to see how each method affects the optic nerve.

To participate in this trial, you need to be between 18 and 65 years old, have a body mass index (BMI) between 18 and 30, and not have any serious health conditions that could make intubation difficult. You also should not have a history of eye problems or conditions that increase pressure in the brain. If you qualify and choose to participate, you can expect to have some ultrasound measurements taken before and after the intubation. This research aims to help improve patient care during surgeries by understanding the best ways to use lidocaine for numbing.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • ASA class I or II
  • Age 18-65 years
  • BMI 18-30
  • No history or expected difficult intubation
  • No glaucoma or ocular pathology
  • No intracranial pressure increase
  • Exclusion Criteria:
  • ASA class III and above
  • Obesity (BMI \> 30)
  • Difficult intubation history or risk
  • Glaucoma or other ophthalmic pathology
  • History of intracranial pressure increase or prior ophthalmic/intracranial surgery
  • Preoperative sedation
  • Active malignancy or ongoing radiotherapy/chemotherapy

About Ankara City Hospital Bilkent

Ankara City Hospital Bilkent is a leading healthcare institution in Turkey, dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. Equipped with state-of-the-art facilities and a multidisciplinary team of experienced professionals, the hospital fosters a collaborative environment for conducting rigorous scientific investigations. Its commitment to ethical standards and patient safety ensures that all clinical trials are conducted with the highest level of integrity, ultimately contributing to the development of new therapies and enhancing the quality of care provided to patients.

Locations

Ankara, , Turkey

Patients applied

0 patients applied

Trial Officials

İsmail Aytaç, Ass. Prof

Principal Investigator

Ankara City Hospital Bilkent

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported