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Search / Trial NCT06874426

The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Mar 7, 2025

Trial Information

Current as of April 30, 2025

Recruiting

Keywords

Olfactory Dysfunction Trigeminal Dysfunction Endoscopic Endonasal Skull Base Surgery Pituitary Surgery

ClinConnect Summary

This clinical trial is looking at how endoscopic endonasal skull base surgery, a type of surgery done through the nose to remove tumors near the base of the skull, affects a person's sense of smell. Researchers want to understand how often people experience problems with their sense of smell after this surgery and what might cause those issues. They will do this by combining regular patient check-ups with tests that look at the cells involved in smell.

To participate in the study, you need to be an adult who is scheduled for this specific type of surgery. However, if you already have a loss of smell or have had this surgery before, you won't be eligible to take part. The trial is not yet recruiting participants, so it’s still in the planning stages. If you join the study, you can expect to undergo evaluations to assess your sense of smell before and after the surgery, which will help the researchers gather important information about how the surgery might impact this ability.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult patients scheduled for endoscopic endonasal skull base surgery
  • Exclusion Criteria:
  • Pre-existing anosmia
  • Patients has a history of previous endoscopic endonasal skull base surgery

About Universitaire Ziekenhuizen Ku Leuven

Universitaire Ziekenhuizen KU Leuven is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. Affiliated with KU Leuven, one of Europe’s premier universities, the institution integrates cutting-edge scientific inquiry with high-quality patient care. It plays a pivotal role in the development and implementation of clinical trials, fostering collaboration between researchers, healthcare professionals, and industry partners to translate scientific discoveries into effective treatments. The hospital's multidisciplinary approach ensures comprehensive patient safety and ethical standards, positioning it as a trusted sponsor in the realm of clinical research.

Locations

Leuven, Vlaams Brabant, Belgium

Frankfurt, Hessen, Germany

Leiden, Zuid Holland, Netherlands

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported