The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Mar 7, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how endoscopic endonasal skull base surgery, a type of surgery done through the nose to remove tumors near the base of the skull, affects a person's sense of smell. Researchers want to understand how often people experience problems with their sense of smell after this surgery and what might cause those issues. They will do this by combining regular patient check-ups with tests that look at the cells involved in smell.

To participate in the study, you need to be an adult who is scheduled for this specific type of surgery. However, if you already have a loss of smell or have had this surgery before, you won't be eligible to take part. The trial is not yet recruiting participants, so it’s still in the planning stages. If you join the study, you can expect to undergo evaluations to assess your sense of smell before and after the surgery, which will help the researchers gather important information about how the surgery might impact this ability.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients scheduled for endoscopic endonasal skull base surgery
• Exclusion Criteria:
• • Pre-existing anosmia
• • Patients has a history of previous endoscopic endonasal skull base surgery