An Extension Test of Whether to Use Oral Anti-anxiety Drugs (XANAX) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Mar 11, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how well an oral anti-anxiety medication called XANAX works for patients undergoing cataract surgery on their second eye. The main goal is to see if taking XANAX can help reduce feelings of anxiety, pain, and discomfort during the surgery, and improve overall satisfaction with the experience. The trial will involve around 250 participants, aged 18 to 80, who are already enrolled in another study about anxiety and surgery satisfaction. To be eligible, participants should not have any serious health issues that would prevent them from having the surgery or taking XANAX.

Participants in this study can expect to complete some questionnaires about their anxiety and satisfaction before, during, and after the surgery. The researchers will carefully monitor their experiences to find out if XANAX makes the surgery easier for them. This information could help improve the way cataract surgeries are performed in the future, providing a safer and more comfortable experience for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age between 18 and 80 years old.
• • 2. Enrolled in "Anxiety and surgery satisfaction for cataract patient with different state anxiety" (Research Ethics Committee Case No.: 202302067MINB).
• • 3. Plan to undergo phacoemulsification and intraocular lens implantation surgery with topical anesthetic on the second eye at the Department of Ophthalmology.
• • 4. Subject who does not have side effect from XANAX.
• Exclusion Criteria:
• • 1. Presence of any surgery contraindications.
• • 2. Presence of any medication contraindications.
• • 3. Inability to provide clear and complete answers to relevant questionnaires, or expression of no preoperative anxiety during the outpatient visit, or scores below 21 on the STAI-S or STAI-T assessment.
• • 4. Regular use of anti-anxiety medications, sleeping pills, or analgesics before the procedure.
• • 5. Pregnancy or breastfeeding during the preoperative period.
• • 6. Severe corneal diseases, overripe cataracts, small pupils, or lens dislocation leading to difficulties in conventional surgery.
• • 7. Patients under surface anesthesia who cannot fully cooperate with the surgical procedure.
• • 8. Pregnant or uncertain pregnancy status (women under 55 years old to be verbally asked by research team members).