Transcatheter Aortic Valve Implantation Registry at the National Research Center for Cardiac Surgery, Nur-Sultan, Kazakhstan

Launched by NATIONAL RESEARCH CENTER FOR CARDIAC SURGERY, KAZAKHSTAN · Mar 11, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different treatments for a heart condition called aortic valve stenosis, which makes it hard for blood to flow from the heart. The researchers want to compare the results of a procedure called transcatheter valve implantation, where a new valve is inserted through a blood vessel, to traditional surgical aortic valve replacement, where the heart is opened to replace the valve. By gathering and analyzing data from patients in Kazakhstan who have undergone these procedures, the study aims to better understand how effective each treatment is for patients with this condition.

To participate in the trial, patients must be between the ages of 65 and 74, have severe aortic stenosis that causes symptoms like shortness of breath or fatigue, and provide written consent to take part. However, individuals with active heart infections or those who have had a stroke in the last three months cannot join. Participants can expect to contribute to valuable research that may help improve treatment options for future patients with aortic valve stenosis. This study is currently recruiting participants, so there is an opportunity for eligible patients to get involved.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients has given written informed Concent for study participation prior to procedure
• • Patients with Aortic Valve stenosis
• • Patients has severe degenerative or congenital aortic stenosis.
• • Patients has symptomatic aortic stenosis as demonstrated by NYHA II or greater
• Exclusion Criteria:
• • Patients has active endocarditis
• • Patients has history of cerebral vascular accident or transient ischemic attack within the past 3 months