Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease

Launched by JIANI WU · Mar 7, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of acupuncture and moxibustion on improving motor symptoms in patients with early-stage Parkinson's Disease (PD). The researchers aim to find out if a specific acupuncture method can help reduce symptoms like tremors, stiffness, and slow movement, which are common in PD. The trial will involve 90 participants who are between 30 and 80 years old and have mild to moderate PD. To qualify, individuals must have a confirmed diagnosis of PD and be able to provide informed consent. Those with certain health issues or previous treatments related to PD may not be eligible.

Participants in the trial will be randomly assigned to one of two groups. One group will receive the acupuncture and moxibustion treatment, while the other will receive a sham treatment that mimics acupuncture but does not target the actual acupuncture points. Both groups will receive treatment three times a week for eight weeks, followed by a follow-up period. Throughout the study, the researchers will closely monitor the participants' progress and any changes in their symptoms to determine if the acupuncture method is effective and safe. This trial could provide valuable insights into new ways to manage Parkinson's symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Participants must meet all of the following criteria:
• • 1. Diagnosed with Parkinson's disease (PD) according to the 2016 Chinese 2. Diagnostic Criteria for Parkinson's Disease.
• • 3. Hoehn-Yahr stage \<3 (mild to moderate PD). 4. Age between 30 and 80 years (inclusive). 5. Signed informed consent indicating voluntary participation.
• Exclusion Criteria:
• Participants meeting any of the following criteria will be excluded:
• • 1. Diagnosed with Parkinson-plus syndromes or other secondary parkinsonism.
• • 2. Prior history of deep brain stimulation (DBS) surgery.
• • 3. Severe cerebrovascular disease, brain trauma, or history of craniotomy.
• • 4. Severe dementia or psychiatric disorders that prevent cooperation with study procedures.
• • 5. Severe coagulation disorders.
• • 6. Presence of severe systemic organ dysfunction (cardiac, pulmonary, hepatic, renal, endocrine, or metabolic disorders).
• • 7. Pregnant or breastfeeding women.
• • 8. History of allergic reaction to acupuncture or moxibustion.
• • 9. Prior treatment with Chinese medicine (herbal medicine, proprietary Chinese medicine, or acupuncture) for Parkinson's disease within the past three months.
• • Participation in another clinical trial within the past three months.